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This calculator determines the Diphenhydramine dose for treating allergic reactions, using a concentration of Diphenhydramine 6.25 mg / 5 mL, based on the patient’s age group:
Dose in mL and mg (based on Diphenhydramine component):
Children under 2 years: Consult a doctor before use.
Children 2 to 5 years: 5 ml (6.25 mg) po every 4 to 6 hours prn [Max 30 ml (37.5 mg) per day]
Children 6 to 12 years: 10 ml (12.5 mg) to 20 ml (25 mg) po every 4 to 6 hours prn [Max 120 ml (150 mg) per day]
Adults: Usual dose is 25 to 50 mg po q4-6h prn [Max 300 mg/day]
Where:
Administer as needed (prn) every 4 to 6 hours for allergy symptoms, not exceeding the maximum daily dose. ⚠️ Always consult a healthcare provider.
Select the patient’s age group from the dropdown and click "Calculate." The calculator provides the dose in mL and mg for children (under 2 years, 2 to 5 years, or 6 to 12 years) and includes the adult dose.
Example: Children 2 to 5 years:
Dosage:
5 ml (6.25 mg) po every 4 to 6 hours prn [Max 30 ml (37.5 mg) per day]
Adults Dosage:
Usual dose is 25 to 50 mg po q4-6h prn [Max 300 mg/day]
Calculations must be re-checked and should not be used alone...
Consult a healthcare provider before administering.
Diphenhydramine (Children’s Benadryl) treats allergic reactions, such as hay fever, hives, and itching, and can also be used for mild sleep aid or motion sickness.
Every 4 to 6 hours as needed (prn): Children 2 to 5 years: 5 ml (6.25 mg), Children 6 to 12 years: 10–20 ml (12.5–25 mg), Adults: 25–50 mg, not exceeding the maximum daily dose.
Consult a doctor, as Diphenhydramine is not typically recommended for children under 2 years without medical supervision.
Usual dose is 25 to 50 mg po q4-6h prn [Max 300 mg/day].
Be cautious—other concentrations like 12.5 mg/5 ml or 50 mg/30 ml exist. This calculator is for 6.25 mg/5 ml only. Always check the label and consult a healthcare provider.